Copper Peptide Serum with 1% GHK-Cu peptide, Argireline and Matrixyl 3000
I’m half way through my first bottle and I’m sold. Signing up for auto delivery! This peptide serum contains everything you want and nothing you don’t:. All three major types of anti aging peptides in one bottle: copper peptides, signaling peptides, and neurotransmitter peptides. Carried in glycerin. Short list of ingredients: no oils, fragrance, comedogenic ingredients, or FA triggers. Great value at $28 a bottle. I saw immediate hydration and increased glow, no irritation. I use it in the AM on clean skin, folllowed by niacinamide, moisturizer, and sunscreen. Sunscreen goes on more smoothly when I use it, which is a bonus. Long term use of these types of peptides may help support collagen production, so a worthy addition to my routine.
I like the product. Fine lines it works well deeper lines is questionable
I used this for a week now so it's too soon to say if it does anything. but it absorbs easily without feeling greesy or sticky. I like it so far. it does feel like skin feel tighter right after I apply it.
I can definitely recommend this product. I just purchased my second bottle. I am seeing results and my skin is glowing and appears more youthful. I like how easy it is to implement in my daily skin regiment too!
Its working for me. I see some changes. I’m glad I am not allergic since I have sensitive skin. I would definitely make it my routine and buy it again.
I like the products but I haven’t noticed any changes in my skin yet.
Love!
I've been using copper peptide for a year now, every evening. Your vitamin C serum is in the morning. This routine has made a noticeable difference in firmness. Being patient and consistent is the ticket. Thank you !
I have used the product for a couple of weeks and I noticed that my dark spots are starting to fade and my skin looks brighter.
I had a reaction to the copper peptide. This may be just me however I had pustules appear day after and had incidences of agitation.
Tightens everything up!
On my second bottle and haven’t seen a significant difference!
This product is a standout addition to your lineup. It consistently improves skin complexion and dramatically softens deep-set expression lines, including forehead wrinkles and '11s.' Paired with retinal, it yields remarkable results at an unbeatable price point.
Great serum - right formula for purpose
I love this stuff! I am in my 60s and have been using this product for about 6 weeks. I can really tell a difference in the texture of my skin. It is smoother and firmer.
I haven’t been using it long enough to know if it’s helping but I did just order another bottle. I wish it came in greater quantity.
Loving it so far!
My face and skin looks so refreshed.
Too soon to notice
O results up till now
Great product
Actually works. Only use 2 drops every night after my shower before bed. Skin looks great already. Scarring is reduced and acne too
Love this so far. On my second bottle.
Easy to use. Too early to tell its benefits.
Just started 3 nights ago. No irritation, a bit sticky formula. Looks like the picture. Hopefully will see some results.
I just started using this product approximately two weeks ago. The minute I put it on I feel a tingling that I’ve never experienced with any other products like this. So far, I have no complaints. Very pleased with the product.
I have tried other products three times longer with less results than what this product has done. In two weeks I am already noticing tighter/more firm skin!
Love, love, love!!
I never received the Copper peptides. I was sent Vitamin C instead. I do love the vitamin C though!
I've never used copper peptides so I have nothing to compare it to.It looks the same as the bottle shown when I ordered it on the website.Have used it for about two weeks every third night don't see much difference.
Love it!
Copper Peptide Serum with 1% GHK-Cu peptide, Argireline and Matrixyl 3000
Copper Peptide Serum
1% GHK-Cu + Matrixyl 3000 + Argireline
A concentrated multi-peptide serum formulated with 1% GHK-Cu (Copper Tripeptide-1) alongside complementary signal peptides to support firmer, smoother-looking skin and improve the appearance of fine lines and age-related changes in skin texture.
What Makes This Formula Different?
Not all peptide serums contain the same peptides—or disclose their concentrations.
Dr. Brenner Copper Peptide Serum combines 1% GHK-Cu with multiple complementary peptides in a lightweight, fragrance-free serum.
This formula includes:
- 1% GHK-Cu (Copper Tripeptide-1) — a naturally occurring copper-binding peptide studied for its role in skin repair and extracellular-matrix remodeling
- Matrixyl 3000 — a peptide complex containing Palmitoyl Tripeptide-1 and Palmitoyl Tetrapeptide-7
- Argireline (Acetyl Hexapeptide-8) — a cosmetic peptide commonly used in formulas targeting the appearance of expression lines
- Palmitoyl Pentapeptide-4 — a signal peptide used in anti-aging skincare formulations
No fragrance. No essential oils.
How Does This Serum Work?
GHK-Cu has been investigated for biological processes relevant to aging skin, including tissue remodeling, wound repair, antioxidant activity, and extracellular-matrix production.
The complementary peptides in the formula target additional pathways associated with the appearance of aging skin.
With consistent use, the formula is designed to help:
- Improve the appearance of fine lines
- Support firmer, smoother-looking skin
- Improve visible skin texture
- Support overall skin resilience and quality
Changes involving skin structure occur gradually, so consistent use is more important than expecting immediate results.
Who Is It For?
This serum is designed for concerns including:
- Fine lines and wrinkles
- Loss of firmness
- Uneven or rough skin texture
- Visible signs of skin aging
- Skin that would benefit from a peptide-focused routine
Suitable for a wide range of skin types. Those with particularly reactive skin should introduce any new active product gradually.
Why GHK-Cu?
GHK-Cu is a naturally occurring copper-binding peptide found in the human body.
Its biological activity has made it an area of scientific interest in research involving tissue repair, extracellular-matrix remodeling, and skin aging.
Dr. Brenner Copper Peptide Serum contains 1% GHK-Cu (Copper Tripeptide-1) and clearly identifies the concentration rather than simply listing “copper peptides” as a marketing claim.
How to Use
Apply 2–3 drops to clean, dry skin once daily.
Follow with moisturizer as needed.
Copper peptides can be incorporated into a routine alongside other skincare actives. If your routine contains multiple high-strength products or your skin is easily irritated, introducing them at different times can simplify your routine and help identify sources of irritation.
When Will I See Results?
Copper peptides should not be expected to produce dramatic changes overnight.
Changes in skin texture, firmness, and the appearance of fine lines generally develop gradually with consistent use over weeks to months.
Results vary depending on skin condition, routine, and consistency of use.
Frequently Asked Questions
What is GHK-Cu?
GHK-Cu is a copper-binding tripeptide also known in cosmetic ingredient labeling as Copper Tripeptide-1. It has been studied for biological activity relevant to tissue repair and skin aging.
Why is the serum blue?
The characteristic blue color comes from the copper-peptide complex itself.
Does this serum contain 1% GHK-Cu?
Yes. Dr. Brenner Copper Peptide Serum is formulated with 1% GHK-Cu (Copper Tripeptide-1).
Can I use copper peptides with Vitamin C?
Both can be incorporated into a skincare routine. A simple approach is to use Vitamin C in the morning and copper peptides in the evening, particularly if you prefer not to layer multiple active serums at once.
Can I use copper peptides with retinoids?
They can be incorporated into the same overall skincare routine. If your skin is sensitive or your retinoid causes irritation, using the products at different times or on alternate nights can make the routine easier to tolerate.
Why Dr. Brenner Labs
Our approach is simple:
- Evidence-backed active ingredients
- Meaningful concentrations
- Purposeful formulations
- Transparent ingredient information
- Responsible skincare claims
We focus on formulation choices grounded in skincare science rather than marketing trends.
Related Research
Copper Peptides for Skin: What Does the Research Actually Show? →
Ingredients: Deionized Water, Glycerin, Propanediol 1,3, Dimethyl Isosorbide, Polyacrylate Crosspolymer-6, Copper Tripeptide-1, Matrixyl 3000 (Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7), Argireline (Acetyl Hexapeptide-8), Palmitoyl Pentapeptide-4, Phenoxyethanol, Caprylyl Glycol.
Reviews
I’m half way through my first bottle and I’m sold. Signing up for auto delivery! This peptide serum contains everything you want and nothing you don’t:. All three major types of anti aging peptides in one bottle: copper peptides, signaling peptides, and neurotransmitter peptides. Carried in glycerin. Short list of ingredients: no oils, fragrance, comedogenic ingredients, or FA triggers. Great value at $28 a bottle. I saw immediate hydration and increased glow, no irritation. I use it in the AM on clean skin, folllowed by niacinamide, moisturizer, and sunscreen. Sunscreen goes on more smoothly when I use it, which is a bonus. Long term use of these types of peptides may help support collagen production, so a worthy addition to my routine.
I like the product. Fine lines it works well deeper lines is questionable
I used this for a week now so it's too soon to say if it does anything. but it absorbs easily without feeling greesy or sticky. I like it so far. it does feel like skin feel tighter right after I apply it.
I can definitely recommend this product. I just purchased my second bottle. I am seeing results and my skin is glowing and appears more youthful. I like how easy it is to implement in my daily skin regiment too!
Its working for me. I see some changes. I’m glad I am not allergic since I have sensitive skin. I would definitely make it my routine and buy it again.
I’m half way through my first bottle and I’m sold. Signing up for auto delivery! This peptide serum contains everything you want and nothing you don’t:. All three major types of anti aging peptides in one bottle: copper peptides, signaling peptides, and neurotransmitter peptides. Carried in glycerin. Short list of ingredients: no oils, fragrance, comedogenic ingredients, or FA triggers. Great value at $28 a bottle. I saw immediate hydration and increased glow, no irritation. I use it in the AM on clean skin, folllowed by niacinamide, moisturizer, and sunscreen. Sunscreen goes on more smoothly when I use it, which is a bonus. Long term use of these types of peptides may help support collagen production, so a worthy addition to my routine.
I like the product. Fine lines it works well deeper lines is questionable
I used this for a week now so it's too soon to say if it does anything. but it absorbs easily without feeling greesy or sticky. I like it so far. it does feel like skin feel tighter right after I apply it.
I can definitely recommend this product. I just purchased my second bottle. I am seeing results and my skin is glowing and appears more youthful. I like how easy it is to implement in my daily skin regiment too!
Its working for me. I see some changes. I’m glad I am not allergic since I have sensitive skin. I would definitely make it my routine and buy it again.
I like the products but I haven’t noticed any changes in my skin yet.
Love!
I've been using copper peptide for a year now, every evening. Your vitamin C serum is in the morning. This routine has made a noticeable difference in firmness. Being patient and consistent is the ticket. Thank you !
I have used the product for a couple of weeks and I noticed that my dark spots are starting to fade and my skin looks brighter.
I had a reaction to the copper peptide. This may be just me however I had pustules appear day after and had incidences of agitation.
Tightens everything up!
On my second bottle and haven’t seen a significant difference!
This product is a standout addition to your lineup. It consistently improves skin complexion and dramatically softens deep-set expression lines, including forehead wrinkles and '11s.' Paired with retinal, it yields remarkable results at an unbeatable price point.
Great serum - right formula for purpose
I love this stuff! I am in my 60s and have been using this product for about 6 weeks. I can really tell a difference in the texture of my skin. It is smoother and firmer.
I haven’t been using it long enough to know if it’s helping but I did just order another bottle. I wish it came in greater quantity.
Loving it so far!
My face and skin looks so refreshed.
Too soon to notice
O results up till now
Great product
Actually works. Only use 2 drops every night after my shower before bed. Skin looks great already. Scarring is reduced and acne too
Love this so far. On my second bottle.
Easy to use. Too early to tell its benefits.
Just started 3 nights ago. No irritation, a bit sticky formula. Looks like the picture. Hopefully will see some results.
I just started using this product approximately two weeks ago. The minute I put it on I feel a tingling that I’ve never experienced with any other products like this. So far, I have no complaints. Very pleased with the product.
I have tried other products three times longer with less results than what this product has done. In two weeks I am already noticing tighter/more firm skin!
Love, love, love!!
I never received the Copper peptides. I was sent Vitamin C instead. I do love the vitamin C though!
I've never used copper peptides so I have nothing to compare it to.It looks the same as the bottle shown when I ordered it on the website.Have used it for about two weeks every third night don't see much difference.
Love it!